Monday, July 9, 2012

Missouri Cures: Diabetes Reversed In Mice Thanks To Stem Cell Transplant

Canadian scientists were able to reverse diabetes in mice with a human stem cell transplant, igniting hopes for a cure for the widespread disease -- caused by the failure of the pancreas to produce enough insulin to stabilize blood sugar levels -- in humans.
International Business Times - A paper outlining the work, led by Timothy Kieffer of the University of British Columbia and conducted in partnership with New Jersey-based company BetaLogics, appeared in the journal Diabetes on Tuesday.
Diabetic mice were weaned off of insulin after receiving the pancreatic stem cell transplant, which restarted the cycle in which insulin production rises or falls based on blood sugar levels.  Three to four months later, the mice could maintain healthy blood sugar levels even after being fed a lot of sugar.
"We are very excited by these findings, but additional research is needed before this approach can be tested clinically in humans," Kieffer said in a statement on Tuesday.
The researchers cautioned that their study used mice that had a suppressed immune system, the better to prevent rejection of the transplanted cells.

Missouri Cures: Diabetes Reversed In Mice Thanks To Stem Cell Transplant

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