Tuesday, September 13, 2011

Taking painkillers long-term 'triples risk of kidney cancer'

People who take anti inflammatory drugs like ibuprofen for more than a decade are tripling their risk of kidney cancer, say scientists.

A study of over 125,000 participants found those who regularly took over the counter anti-inflammatories were 51 per cent more likely to develop the disease.

But the researchers found those who used them for over a decade, such as arthritis sufferers, were almost three times more likely to suffer renal cell cancer (RCC), the most common form of kidney cancer.

Aspirin was the only member among the group of medications - known as NSAIDS (non-steroidal anti-inflammatory drugs) - that was found to be safe.

Dr Eunyoung Cho, of Harvard Medical School, Boston, and colleagues said: 'In these large prospective studies of women and men, we found that use of non-aspirin NSAIDs was associated with an elevated risk of renal cell cancer, especially among those who took them for a long duration.'

Renal cancer accounts for two per cent of all cancers diagnosed in the UK. It is difficult to treat with around one in three surviving the disease.

Pain-relieving medications - or analgesics - are among the most commonly used groups of drugs and some appear to have protective effects against cancer.

But writing in Archives of Internal medicine the researchers said: 'However some epidemiologic data, mainly from case-control studies, suggest an association between analgesic use and an increased risk of RCC.'

So Dr Cho and colleagues analysed data on 77,525 women and 49,403 men whose use of aspirin and other NSAIDs was recorded for up to twenty years during which time 333 developed renal cell cancer.

Source and More:

No comments: